When the most important friend in her life seems to have disappeared without a trace, Elena Greco, a now-elderly woman immersed in a house full of books, turns on her computer and starts writing the story of their friendship.

'L'amica geniale' is acclaimed for its emotional depth, intricate characters, and faithful adaptation. The series is celebrated for its cinematography, period detail, and nuanced portrayal of friendship. Critics praise the realistic depiction of working-class life, powerful performances, and exploration of societal themes. Some find the pacing slow and characters unlikable, yet many consider it a cinematic masterpiece.