Pakistan-born comedian Kumail Nanjiani and grad student Emily Gardner fall in love but struggle as their cultures clash. When Emily contracts a mysterious illness, Kumail finds himself forced to face her feisty parents, his family's expectations, and his true feelings.

Funny, heartfelt, and intelligent, The Big Sick uses its appealing leads and cross-cultural themes to prove the standard rom-com formula still has some fresh angles left to explore.