Lou Clark, a directionless 26-year-old from the English countryside, takes a job at the local castle as a caregiver and companion to a wealthy young banker, Will Traynor. Wheelchair-bound from an accident two years prior, the once adventurous Will has all but given up — that is until Lou determines to show him that life is worth living.

Me Before You benefits from Emilia Clarke and Sam Claflin's alluring chemistry, although it isn't enough to compensate for its clumsy treatment of a sensitive subject.