Brandon, a thirty-something man living in New York, eludes intimacy with women but feeds his deepest desires with a compulsive addiction to sex. When his younger sister temporarily moves into his apartment, stirring up bitter memories of their shared painful past, Brandon's life, like his fragile mind, gets out of control.

Boasting stellar performances by Michael Fassbender and Carey Mulligan, Shame is a powerful plunge into the mania of addiction affliction.