An unprecedented series of violent tornadoes is sweeping across Oklahoma. Tornado chasers, headed by Dr. Jo Harding, attempt to release a groundbreaking device that will allow them to track them and create a more advanced warning system. They are joined by Jo's soon to be ex-husband Bill, a former tornado chaser himself, and his girlfriend Melissa.

A high-concept blockbuster that emphasizes special effects over three-dimensional characters, Twister's visceral thrills are often offset by the film's generic plot.